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VOXELOTOR
SynDRA canonical compound SYN0039287 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Mechanism of action | hemoglobin modulator |
|---|
All known targets
- CYP2C8
- CYP2C9
- CYP3A4
- HBA1
- HBA2
- HBB
Mechanisms of action (all sources)
- HBA1 POSITIVE MODULATOR
- Hemoglobin HbA positive modulator
- HBA2 POSITIVE MODULATOR
- HBB POSITIVE MODULATOR
- CYP2C8 INHIBITOR
- CYP2C9 INHIBITOR
- CYP3A4 INHIBITOR
- hemoglobin modulator
- HBA2 MODULATOR
- HBA1 INHIBITOR
Drug classes
- Hematologic Agents
- Cytochrome P450 3A4 Inhibitors
- Hemoglobin S Polymerization Inhibitor
- Hemoglobin S Polymerization Inhibitors
ATC classes
- B06A · OTHER HEMATOLOGICAL AGENTS
Cross-references
Synonyms
- GBT440
- oxbryta
- GTX-011
- GBT-440
- Oxbryta
- Hemoglobin Modulators-1
- UNII-3ZO554A4Q8
- 3ZO554A4Q8
- 2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methoxy)benzaldehyde
- 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
- 2-hydroxy-6-((2-(1-(propan-2-yl)-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
- Voxelotor [USAN]
- SCHEMBL15065529
- Voxelotor(GBT440, GTx011)
- MolPort-044-830-677
- FWCVZAQENIZVMY-UHFFFAOYSA-N
- AKOS030526545
- ZINC145969085
- CS-5317
- HY-18681
- DA-44587
- GTX 011
- Voxelotorum
- RefChem:58277
- GTX011
- DTXCID701513522
- MFCD29053764
- Voxelotor (USAN)
- Oxbryta (TN)
- VOXELOTOR [INN]
- GBT-440(Voxelotor)
- Voxelotor (GBT440)
- VOXELOTOR [MI]
- GBT-440(Voxelotor)?
- VOXELOTOR [WHO-DD]
- orb1299687
- VOXELOTOR [ORANGE BOOK]
- GTPL10559
Reported adverse events
- Abdominal pain
- Angioedema
- Drug hypersensitivity
- Headache
- Nausea
- Rash
- Drug reaction with eosinophilia and systemic symptoms
- Hypersensitivity
- Pyrexia
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