← SynDRA

RIPRETINIB

SynDRA canonical compound SYN0039335 — structure-anchored drug synonym record

All known targets

• KIT
• PDGFRA
• CSF1R
• KDR
• PDGFRB
• TEK

Mechanisms of action (all sources)

• KIT INHIBITOR
• Stem cell growth factor receptor inhibitor
• PDGFRA INHIBITOR
• Platelet-derived growth factor receptor alpha inhibitor
• PDGFR tyrosine kinase receptor inhibitor
• receptor tyrosine protein kinase inhibitor

Drug classes

• Platelet-derived Growth Factor alpha Receptor Inhibitors
• Stem Cell Factor (KIT) Receptor Inhibitors
• Kinase Inhibitor
• P-Glycoprotein Inhibitors
• Cytochrome P450 2C8 Inhibitors
• Breast Cancer Resistance Protein Inhibitors

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 71584930
• ChEMBL: CHEMBL4216467
• DrugBank: DB14840
• KEGG: D11353
• RxNorm: 2369389
• Wikipedia: Ripretinib
• TTD: D09AAK

Synonyms

• qinlock
• DCC-2618
• Qinlock
• Ripretinib [USAN]
• UNII-9XW757O13D
• GTPL9175
• SCHEMBL14999718
• 9XW757O13D
• HY-112306
• CS-0044835
• N-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-N'-phenylurea
• 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea
• Urea, N-(4-bromo-5-(1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl)-2-fluorophenyl)-N'-phenyl-
• DCC2618
• ripretinibum
• RefChem:57787
• DTXCID101513524
• KIT/PDGFR Inhibitor DCC-2618
• Ripretinib free base
• Ripretinib (DCC-2618)
• C24H21BrFN5O2
• Quinlock
• Qinlock (TN)
• MFCD31657437
• RIPRETINIB [MI]
• RIPRETINIB [INN]
• Ripretinib (JAN/USAN)
• RIPRETINIB [WHO-DD]
• Ripretinib (DCC-2618)?
• orb1298897
• RIPRETINIB [ORANGE BOOK]
• SCHEMBL29362351
• GLXC-15506
• HMS5086E13
• EX-A4883
• BDBM50609506
• EBC-27255
• s8757

Reported adverse events

• Alopecia
• Fatigue
• Headache
• Hypertension
• Myalgia
• Nausea
• Stomatitis
• Abdominal pain
• Arthralgia
• Asthenia
• Constipation
• Dry skin