MILADEMETAN

SynDRA canonical compound SYN0039365 — structure-anchored drug synonym record

Clinical phase	Phase 1
Primary target(s)	MDM2
Mechanism of action	MDM inhibitor

All known targets

F8
MDM2

Mechanisms of action (all sources)

MDM inhibitor

Cross-references

PubChem CID: 73297272
ChEMBL: CHEMBL4292264
DrugBank: DB15257
KEGG: D12621
Wikipedia: Milademetan
TTD: DGB7W9

Synonyms

DS-3032
Mdm2 inhibitor ds-3032
DS3032a
RAIN-32
(3'R,4'S,5'R)-N-((3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl)-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-indole)-5'-carboxamide
(3'R,4'S,5'R)-N-[(3R,6S)-6-carbamoyloxan-3-yl]-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide
(3'R,4'S,5'R)-N-[(3R,6S)-6-carbamoyltetrahydro-2H-pyran-3-yl]-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide
2,6-Anhydro-5-((((3'R,4'S,5'R)-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-1'',2''-dihydro-4,4-dimethyl-2''-oxodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-(3H)indol)-5'-yl)carbonyl)amino)-3,4,5-trideoxy-L-erythro-hexonamide
AKOS040733738
BDBM50467678
CHEMBL4292264
CS-0021065
DB15257
DS3032
DS3032b
DS-3032B
EX-A6155
GTPL12941
HY-101266
L-Erythro-hexonamide, 2,6-anhydro-5-((((3'R,4'S,5'R)-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-1'',2''-dihydro-4,4-dimethyl-2''-oxodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-(3H)indol)-5'-yl)carbonyl)amino)-3,4,5-trideoxy-
L-erythro-Hexonamide, 2,6-anhydro-5-[[[(3'R,4'S,5'R)-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-1'',2''-dihydro-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-[3H]indol]-5'-yl]carbonyl]amino]-3,4,5-trideoxy-
MDM2 inhibitor DS-3032
MILADEMETAN [INN]
MILADEMETAN [USAN]
MILADEMETAN [WHO-DD]
MS-30758
NSC800893
NSC-800893
Q27896170
R3I80TLN7S
RYAYYVTWKAOAJF-QISPRATLSA-N
SCHEMBL12527208
UNII-R3I80TLN7S
YFC56847
milademetanum
RefChem:158856
Milademetan (USAN/INN)
C30H34Cl2FN5O4
orb1709129

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