← SynDRA

CILOFEXOR

SynDRA canonical compound SYN0039708 — structure-anchored drug synonym record

All known targets

• NR1H4
• EPHA2

Mechanisms of action (all sources)

• NR1H4 AGONIST
• Bile acid receptor FXR agonist
• EPHA2 INHIBITOR
• FXR agonist

Cross-references

• PubChem CID: 71228883
• ChEMBL: CHEMBL4297613
• DrugBank: DB15168
• PDB: 811
• Wikipedia: Cilofexor
• TTD: DBND71

Synonyms

• GS-9674
• PX-104
• PX104
• GS 9674
• UNII-YUN2306954
• 1418274-28-8 (free acid)
• YUN2306954
• 2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid
• 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]phenyl]-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid
• Cilofexor [INN]
• Cilofexor (GS(c)\\9674)
• CHEMBL4297613
• SCHEMBL14641986
• GTPL10644
• BCP29283
• BDBM50511109
• GS9674
• s6547
• DB15168
• example 13/9 [US10485795B2]
• HY-109083
• CS-0039260
• 2-(3-(2-Chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl)methoxy)phenyl)-3-hydroxy-1-azetidinyl)-4-pyridinecarboxylic acid
• 4-Pyridinecarboxylic acid, 2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl)methoxy)phenyl)-3-hydroxy-1-azetidinyl)-
• cilofexorum
• RefChem:126143
• Cilofexor?
• MFCD31731099
• Cilofexor [WHO-DD]
• C28H22Cl3N3O5
• Cilofexor (GS(c)\9674)
• orb1299821
• SCHEMBL29358579
• SCHEMBL29709708
• TGC27428
• AKOS040759138
• AC-35893
• DA-72217
• MS-30487