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SELITRECTINIB
SynDRA canonical compound SYN0039720 — structure-anchored drug synonym record
Clinical phase Phase 1/Phase 2 Primary target(s) NTRK1 Mechanism of action protein tyrosine kinase inhibitor
All known targets
Mechanisms of action (all sources)
NTRK1 INHIBITOR
Neurotrophic tyrosine kinase receptor inhibitor
NTRK2 INHIBITOR
NTRK3 INHIBITOR
tyrosine kinase inhibitor
Drug classes
Cross-references
Synonyms
LOXO-195
LOXO 195
OEBIHOVSAMBXIB-SJKOYZFVSA-N
LOXO195
UNII-0J45910S3X
0J45910S3X
LOXO-195 (S racemic)
SCHEMBL18823882
EX-A1873
HY-101977
CS-0022378
Cas registry number 2097002-61-2 ~1~1 C20 H21 F N6 O 10H-5,7-ethenopyrazolo(3,4-d)pyrido(2,3-k)pyrrolo(2,1-m)(1,3,7)triazacyclotridecin-10-one, 17-fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-, (12R,18bR)-
12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR,10R)-
(13E,14E,22R,6R
BAY-2731954
selitrectinibum
RefChem:182327
TRK Inhibitor LOXO-195
LOXO 195(Selitrectinib)
Selitrectinib (LOXO-195)
Selitrectinib(LOXO-195)
MFCD31620755
SelitrectinibLOXO-195
Selitrectinib (Standard)
SELITRECTINIB [INN]
SELITRECTINIB [WHO-DD]
C20H21FN6O
orb1299822
SCHEMBL29673979
GTPL10314
BDBM50507492
NSC809970
AKOS037648883
HY-101977R
NSC-809970
AC-32662
BS-15941
DA-67532
example 28 [WO2017075107A1]
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Data harmonized from ChEMBL, DrugBank, DrugCentral, Guide to Pharmacology, LINCS/CMap, PharmGKB/PubChem MeSH, Repurposing Hub, TTD, and Open Targets. Part of the SynDRA drug synonym hub.