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MITAPIVAT
SynDRA canonical compound SYN0039807 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | PKM |
|---|
| Mechanism of action | pyruvate kinase isozyme activator |
|---|
All known targets
Mechanisms of action (all sources)
- PKLR ACTIVATOR
- Pyruvate kinase isozymes R/L activator
- PKLR POSITIVE ALLOSTERIC MODULATOR
- PKM ACTIVATOR
- pyruvate kinase isozyme activator
Drug classes
- Enzyme Activators
- P-Glycoprotein Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2C8 Inducers
- Cytochrome P450 2B6 Inducers
- Cytochrome P450 3A Inducers
- Pyruvate Kinase Activator
- Pyruvate Kinase Activators
- UGT1A1 Inducers
ATC classes
- B06A · OTHER HEMATOLOGICAL AGENTS
Cross-references
Synonyms
- mitapivat sulfate
- pyrukynd
- AG-348 sulfate hydrate
- AG-348
- Pkr-in-1
- AG 348
- 2WTV10SIKH
- PKR-IN-1
- AG348
- mitapivatum
- RefChem:58117
- PK-R Activator AG-348
- Red Cell Pyruvate Kinase Activator AG-348
- PKM2 activator 1020
- Mitapivat?
- MITAPIVAT [INN]
- UNII-2WTV10SIKH
- MITAPIVAT [WHO-DD]
- orb1303046
- SCHEMBL2702716
- SCHEMBL30406607
- C24H26N4O3S
- GTPL10473
- GLXC-15319
- EX-A2626
- KAC07517
- BDBM50597714
- s6508
- AKOS030526365
- PKR-IN-1; PKM2 activator 1020
- AT10134
- CS-3895
- NCGC00386704-01
- NCGC00386704-02
- NCGC00386704-03
- AC-36187
- compound 80a [WO2011002817A1]
- DA-65482
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