← SynDRA

LAZERTINIB

SynDRA canonical compound SYN0039918 — structure-anchored drug synonym record

All known targets

• EGFR
• JAK3
• KDR
• SYK

Mechanisms of action (all sources)

• EGFR INHIBITOR
• Epidermal growth factor receptor erbB1 inhibitor
• JAK3 INHIBITOR
• KDR INHIBITOR
• SYK INHIBITOR
• tyrosine kinase inhibitor

Drug classes

• Tyrosine Kinase Inhibitors

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 121269225
• ChEMBL: CHEMBL4558324
• DrugBank: DB16216
• KEGG: D11980
• RxNorm: 2691150
• Wikipedia: Lazertinib
• TTD: DR3FA8

Synonyms

• YH25448
• C-18112003-G
• GNS-1480
• GNS1480
• JNJ-73841937-AAA
• YH-25448
• JNJ-73841937
• GNS 1480
• YH 25448
• UNII-4A2Y23XK11
• 4A2Y23XK11
• N-(5-((4-(4-((Dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl)amino)-4-methoxy-2-morpholinophenyl)acrylamide
• N-[5-[[4-[4-[(dimethylamino)methyl]-3-phenylpyrazol-1-yl]pyrimidin-2-yl]amino]-4-methoxy-2-morpholin-4-ylphenyl]prop-2-enamide
• N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin-4-yl)phenyl}prop-2-enamide
• Lazertinib [USAN]
• Lazertinib [INN]
• Lazertinib (YH25448,GNS-1480)
• CHEMBL4558324
• SCHEMBL17670400
• GTPL10136
• BCP30440
• EX-A1912
• s8724
• WHO 10587
• CCG-270023
• YH-25448;GNS-1480
• BS-15742
• Compound 73 [WO2016060443A2]
• HY-109061
• AK00779508
• CS-0032992
• A16827
• 2-Propenamide, N-(5-((4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)-2-pyrimidinyl)amino)-4-methoxy-2-(4-morpholinyl)phenyl)-
• CN(C)CC=1C(=NN(C=1)C1=NC(=NC=C1)NC=1C(=CC(=C(C=1)NC(C=C)=O)N1CCOCC1)OC)C1=CC=CC=C1
• N-(5-((4-(4-((Dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)-2-pyrimidinyl)amino)-4-methoxy-2-(4-morpholinyl)phenyl)acrylamide
• N-(5-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-ylamino)-4-methoxy-2-morpholinophenyl)acrylamide
• Lazcluze
• lazertinibum
• RefChem:798668