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NAPORAFENIB
SynDRA canonical compound SYN0039934 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | RAF1 |
|---|
| Mechanism of action | RAF inhibitor |
|---|
All known targets
- RAF1
- BRAF
- DDR1
- DDR2
- PDGFRB
Mechanisms of action (all sources)
- RAF1 INHIBITOR
- B-raf/RAF proto-oncogene serine/threonine-protein kinase inhibitor
- BRAF INHIBITOR
- DDR1 INHIBITOR
- DDR2 INHIBITOR
- PDGFRB INHIBITOR
- RAF inhibitor
Drug classes
- Antineoplastic Agents
- Protein Kinase Inhibitors
Cross-references
Synonyms
- LXH-254
- LXH254
- ERAS-254
- PAN-RAF INHIBITOR LXH254
- UEPXBTCUIIGYCY-UHFFFAOYSA-N
- SCHEMBL16094629
- BDBM88120
- HY-112089
- CS-0043317
- US9694016, 1156
- N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide
- LXH 254
- Pan-raf inhibitor LXH254
- RefChem:164782
- pan-RAF Kinase Inhibitor LXH254
- Raf Family Kinase Inhibitor LXH254
- LXH254 free base
- Naporafenib [INN]
- K81
- MFCD31657408
- Naporafenib (USAN/INN)
- NAPORAFENIB [USAN]
- NVP-LXH254
- UNII-15JL80DG6H
- NAPORAFENIB [WHO-DD]
- orb1309463
- LXH 254 [WHO-DD]
- SCHEMBL29388317
- SCHEMBL29411709
- SCHEMBL30241122
- GTPL10658
- LXH254?
- C25H25F3N4O4
- GLXC-20142
- EX-A1846
- NSC807047
- s8745
- AKOS037648965
- AT23218
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