← SynDRA

ENCEQUIDAR

SynDRA canonical compound SYN0039995 — structure-anchored drug synonym record

All known targets

• ABCB1
• ABCB4

Mechanisms of action (all sources)

• ABCB1 INHIBITOR
• P-glycoprotein 1 inhibitor
• P glycoprotein inhibitor
• ABCB4 INHIBITOR

Cross-references

• PubChem CID: 11399764
• ChEMBL: CHEMBL4594298
• DrugBank: DB14070
• KEGG: D11782
• TTD: D9UGX7

Synonyms

• Pgp inhibitor hm30181ak
• HM-30181
• HM30181
• HM30181AK
• HM-30181-A
• UNII-K4I4I996O4
• K4I4I996O4
• 849675-66-7 (free base)
• HM-30181A
• N-(2-(2-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide
• HM30181A
• Encequidar [USAN]
• Encequidar (USAN/INN)
• HM-30181 free base
• CHEMBL4594298
• SCHEMBL13822558
• EX-A3429A
• BCP25240
• MFCD25976625
• WHO 10861
• ZINC68014383
• CS-6194
• DB14070
• SB18921
• 4-Oxo-4H-chromene-2-carboxylic acid (2-(2-4-(2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl)-phenyl-2H-tetrazol-5-yl)-4,5-dimethoxy-phenyl)-amide
• AS-35283
• HY-13646
• D11782
• Q27281950
• 4-oxo-4H-chromen-2-carboxylic acid [2-(2-{4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2H-tetrazol-5-yl)-4,5-dimethoxy-phenyl]-amide
• 4H-1-Benzopyran-2-carboxamide, N-[2-[2-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-2H-tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxo-
• N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide
• N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxochromene-2-carboxamide
• ENCEQUIDAR [INN]
• ENCEQUIDAR [WHO-DD]
• P-GLYCOPROTEIN INHIBITOR HM30181AK
• Oraxol (encequidar methanesulfonate + paclitaxel)
• Oratecan (encequidar methanesulfonate + irinotecan)
• encequidarum