← SynDRA

ADAGRASIB

SynDRA canonical compound SYN0040002 — structure-anchored drug synonym record

All known targets

• KRAS

Mechanisms of action (all sources)

• KRAS INHIBITOR
• GTPase KRas inhibitor
• ras gtpase inhibitor

Drug classes

• Antineoplastic Agents

ATC classes

• L01X · OTHER ANTINEOPLASTIC AGENTS

Cross-references

• PubChem CID: 138611145
• ChEMBL: CHEMBL4594350
• DrugBank: DB15568
• ChEBI: 233309
• KEGG: D12301
• RxNorm: 2625882
• PDB: A1B7W
• Wikipedia: Adagrasib
• TTD: DUQV41

Synonyms

• krazati
• MRTX849
• KRAS G12C INHIBITOR MRTX849
• KRAZATI
• MRTX-849
• ADAGRASIB (MRTX849)
• COMPOUND 20
• MRTX 849
• UNII-8EOO6HQF8Y
• 8EOO6HQF8Y
• 2-((S)-4-(7-(8-Chloronaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-1-(2-fluoroacryloyl)piperazin-2-yl)acetonitrile
• CHEMBL4594350
• SCHEMBL20974691
• GTPL10888
• Kras G12C inhibitor MRTX849
• BCP31538
• EX-A3258
• MFCD32263433
• s8884
• compound 20 [PMID: 32250617]
• BS-16211
• HY-130149
• CS-0105265
• 2-Piperazineacetonitrile, 4-(7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-(((2S)-1-methyl-2-pyrrolidinyl)methoxy)pyrido(3,4-d)pyrimidin-4-yl)-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2S)-
• RefChem:56312
• DTXCID001767019
• Adagrasib [USAN]
• Adagrasib (MRTX849)
• Krazati (TN)
• ADAGRASIB [INN]
• Adagrasib (USAN/INN)
• MRTX849(Adagrasib)?
• ADAGRASIB [WHO-DD]
• C32H35ClFN7O2
• orb1298993
• SCHEMBL29349856
• SCHEMBL29423703
• SCHEMBL29979738