← SynDRA

MOBOCERTINIB

SynDRA canonical compound SYN0040149 — structure-anchored drug synonym record

All known targets

• EGFR
• BLK
• BTK
• ERBB2
• ERBB4
• JAK3
• TXK

Mechanisms of action (all sources)

• EGFR INHIBITOR
• Epidermal growth factor receptor erbB1 inhibitor
• ERBB2 INHIBITOR

Drug classes

• HER1 Antagonists
• Kinase Inhibitor
• Cytochrome P450 3A Inducers
• Antineoplastic Agents
• Tyrosine Kinase Inhibitors

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 118607832
• ChEMBL: CHEMBL4650319
• DrugBank: DB16390
• KEGG: D12001
• Wikipedia: Mobocertinib
• TTD: DI4HA7

Synonyms

• mobocertinib succinate
• exkivity
• TAK-788
• AP32788
• AP-32788
• TAK788
• UNII-39HBQ4A67L
• 39HBQ4A67L
• propan-2-yl 2-[4-{[2-(dimethylamino)ethyl](methyl)amino}-2-methoxy-5-(prop-2-enamido)anilino]-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
• Mobocertinib [INN]
• Mobocertinib [USAN]
• AP 32788
• Mobocertinib (TAK788)
• Mobocertinib(TAK-788)
• SCHEMBL17373133
• GTPL10468
• BDBM368374
• BCP31045
• EX-A3392
• US10227342, Example 10
• MFCD32669806
• NSC825519
• s6813
• TAK-788;AP32788
• WHO 11183
• NSC-825519
• example 94 [WO2015195228A1]
• HY-135815
• CS-0114256
• TAK-788;TAK 788
• 5-Pyrimidinecarboxylic acid, 2-((4-((2-(dimethylamino)ethyl)methylamino)-2-methoxy-5-((1-oxo-2-propen-1-yl)amino)phenyl)amino)-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
• C(C=C)(=O)NC=1C(=CC(=C(C=1)NC1=NC=C(C(=N1)C1=CN(C2=CC=CC=C12)C)C(=O)OC(C)C)OC)N(C)CCN(C)C
• Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
• Isopropyl 2-(5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenylamino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
• Propan-2-yl 2-(5-(acryloylamino)-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyanilino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
• propan-2-yl 2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate
• TAK 788
• RefChem:58463