granisetron

SynDRA canonical compound SYN0041506 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	HTR3A
Mechanism of action	Serotonin receptor antagonist
Indication	nausea \| vomiting
Disease area	gastroenterology

All known targets

HTR3A
CHRNA3
CHRNA4
CHRNB2
CYP3A5
HTR3B
Htr3a
Htr3b
KCNH2
SLC22A2
SLC47A1

Mechanisms of action (all sources)

Serotonin receptor antagonist
HTR3A ANTAGONIST

Drug classes

Serotonin 3 Receptor Antagonists
Serotonin-3 Receptor Antagonist
Antiemetics
Central Nervous System Agents
Gastrointestinal Agents
Neurotransmitter Agents
Peripheral Nervous System Agents
Serotonin 5-HT3 Receptor Antagonists
Serotonin Agents
Serotonin Antagonists

ATC classes

ANTIEMETICS AND ANTINAUSEANTS

Cross-references

PubChem CID: 5284566
ChEMBL: CHEMBL289469
DrugBank: DB00889
ChEBI: CHEBI:5537
KEGG: D00677
PDB: CWB
Wikipedia: Granisetron
LINCS BRD: BRD-K10860596

Synonyms

granisetron monohydrochloride
BRL-43694
sancuso
kevatril
granisetron hydrochloride
granisetron HCl
kytril
Sancuso
Kytril
LY-278584
SID90340785
جرانيسيترون
گرانیسترون
granisétron
グラニセトロン
Granisetrona
Гранісетрон
格拉司琼
Granisetrón

Reported adverse events

Constipation
Headache
Hypersensitivity
Hypertension
Nausea
Vomiting
Dizziness
Dyspepsia
Agitation
Asthenia
Somnolence
Abdominal pain

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