rifampicin

SynDRA canonical compound SYN0041758 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ABCB1 \| CYP2B6 \| CYP2C19 \| CYP2C8 \| CYP3A4 \| CYP3A5 \| NR1I2 \| SLCO1A2 \| SLCO1B1 \| SLCO1B3
Mechanism of action	RNA polymerase inhibitor
Indication	meningitis \| tuberculosis \| tuberculosis, meningitis
Disease area	infectious disease

All known targets

SLCO1B3
SLCO1B1
SLCO1A2
NR1I2
ABCB1
ABCB11
inhA
SNCA
GSTO1
CYP51A1
CYP3A5
CYP3A4

Mechanisms of action (all sources)

RNA polymerase inhibitor
rpoB INHIBITOR

Drug classes

Rifamycin Antibacterial
Anti-Bacterial Agents
Anti-Infective Agents
Antibiotics, Antitubercular
Antitubercular Agents
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 CYP2C19 Inducers
Cytochrome P-450 CYP2C8 Inducers
Cytochrome P-450 CYP2C9 Inducers
Cytochrome P-450 CYP3A Inducers
Enzyme Inhibitors
Leprostatic Agents

ATC classes

DRUGS FOR TREATMENT OF TUBERCULOSIS
DRUGS FOR TREATMENT OF LEPRA

Cross-references

PubChem CID: 135398735
ChEMBL: CHEMBL374478
DrugBank: DB01045
ChEBI: CHEBI:28077
KEGG: D00211

Synonyms

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