eptifibatide

SynDRA canonical compound SYN0041763 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	ITGA2B \| ITGB3
Mechanism of action	platelet aggregation inhibitor
Indication	acute coronary syndrome (ACS) \| acute coronary syndrome (acs), percutaneous coronary intervention (pci) \| percutaneous coronary intervention (PCI)
Disease area	cardiology

All known targets

ITGA2B
ITGB3
ITGA2B; ITGB3

Mechanisms of action (all sources)

ITGB3 INHIBITOR
Integrin alpha-IIb/beta-3 inhibitor
ITGA2B INHIBITOR
platelet aggregation inhibitor
Modulator

Drug classes

Platelet Aggregation Inhibitor
Hematologic Agents
Platelet Aggregation Inhibitors

ATC classes

B01A · ANTITHROMBOTIC AGENTS

Cross-references

PubChem CID: 448812
ChEMBL: CHEMBL1174
DrugBank: DB00063
ChEBI: CHEBI:291902
KEGG: D06888
RxNorm: 75635
Wikipedia: Eptifibatide
TTD: D09ZIO

Synonyms

eftifibatide
integrelin
integrilin
intrifiban
Eptifibatida
Integrelin
Eptifibatide accord
Integrilin
Intrifiban
HS-2011
Integrilin (TN)
SB-1
Sch-60936
N(6)-amidino-N(2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide
N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide
S(1),S(6)-cyclo[N(6)-carbamimidoyl-N(2)-(3-sulfanylpropanoyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide]
L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic (1-6)-disulfide
L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-propyl-,cyclic (1-6)-disulfide
[(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid
2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid
2-[20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid
CHEMBL1174
CHEBI:291902
Eptifibatide Acetate
NA8320J834
NCGC00167505-01
C68-22
2-((3R,11S,17S,20S,25aS)-20-((1H-indol-3-yl)methyl)-3-carbamoyl-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl)acetic acid
L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1-->6)-disulfide
CAS-188627-80-7
EPTIFIBATIDE [INN]
Eptifibatide [INN:BAN]
UNII-NA8320J834
EPTIFIBATIDE [MI]
EPTIFIBATIDE [USAN]
EPTIFIBATIDE [VANDF]
SCHEMBL15781
EPTIFIBATIDE [MART.]

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