octreotide

SynDRA canonical compound SYN0041786 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	GH1 \| SST \| SSTR2 \| SSTR3 \| SSTR5
Mechanism of action	somatostatin receptor agonist
Indication	acromegaly \| carcinoid tumors \| diarrhea
Disease area	endocrinology \| gastroenterology \| oncology

All known targets

SSTR2
SSTR3
SSTR5
GH1
OPRM1
SST
SSTR1
SSTR4
Sstr2
Sstr3
Sstr5

Mechanisms of action (all sources)

somatostatin receptor agonist
SSTR2 BINDER
SSTR2 AGONIST
SSTR3 AGONIST
SSTR5 AGONIST
SSTR4 AGONIST
SSTR1 AGONIST

Drug classes

Somatostatin Receptor Agonists
Somatostatin Analog
Antineoplastic Agents
Antineoplastic Agents, Hormonal
Gastrointestinal Agents

ATC classes

H01C · HYPOTHALAMIC HORMONES

Cross-references

PubChem CID: 448601
ChEMBL: CHEMBL1680
DrugBank: DB00104
ChEBI: CHEBI:7726
KEGG: D00442
RxNorm: 7617
Wikipedia: Octreotide
TTD: D02XIY

Synonyms

longastatin
octreotide acetate
sandostatin
SMS-201-995
sandostatine
Longastatin
Octreotida
Octreotidum
Sandostatine
Octreotida [Spanish]
Octreotide Acetate Salt
Octreotidum [Latin]
DRG-0115
HS-2020
Octreotide-LAR
SAN 201-995
SM 201-995
Sandostatin (TN)
Sandoz 201-995
Octreotide (USAN/INN)
Octreotide [USAN:INN:BAN]
Zacycloicosane-4-carboxamide acetate
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa;10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
SMS 201-995
octreotide (ep monograph)
RWM8CCW8GP
SMS995
SMS-995
CHEBI:7726
Compound 201995
RefChem:59031
SMS 201995
Compound 201-995

Reported adverse events

Hypothyroidism
Vomiting
Cholelithiasis
Anaphylactoid reaction
Pancreatitis
Malabsorption
Dizziness
Dyspepsia
Headache
Back pain
Fatigue
Flatulence

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