guggulsterone

SynDRA canonical compound SYN0043070 — structure-anchored drug synonym record

Primary target(s)	NR1H4
Mechanism of action	Progesterone receptor agonist

All known targets

NR1H4
AR
NR3C1
NR3C2
PGR

Mechanisms of action (all sources)

IKK inhibitor
FXR antagonist
Cholesterol inhibitor
ESR1 AGONIST
Pregnane X receptor agonist
PGR AGONIST
NR1H4 ANTAGONIST

Cross-references

PubChem CID: 53394010
ChEBI: CHEBI:91934
LINCS BRD: BRD-A86109770

Synonyms

Z/E-Guggulsterone
Pregna-4,17-diene-3,16-dione
A4PW148END
RefChem:929953
DTXCID70810153
(17Z)-Pregna-4,17(20)-diene-3,16-dione
SCHEMBL13304392
HMS3268F19
(17E)-Pregna-4,17(20)-diene-3,16-dione
17-Ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione

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