nintedanib

SynDRA canonical compound SYN0086635 — structure-anchored drug synonym record

Primary target(s)	PDGFRB
Mechanism of action	VEGFR inhibitor

All known targets

FGFR1
FGFR3
FLT1
FLT4
KDR
PDGFRA
PDGFRB
FGFR2
FGFR4
LATS1

Mechanisms of action (all sources)

FGFR inhibitor
PDGFR inhibitor
VEGFR inhibitor
FGFR1 INHIBITOR
FGFR2 INHIBITOR
FGFR3 INHIBITOR
FGFR4 INHIBITOR
FLT1 INHIBITOR
FLT4 INHIBITOR
KDR INHIBITOR
LATS1 INHIBITOR
PDGFRA INHIBITOR

Cross-references

PubChem CID: 56965894
ChEMBL: CHEMBL2136735
ChEBI: CHEBI:91413
LINCS BRD: BRD-K49075727

Synonyms

BIBF-1120
3-[[4-[methyl-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylic acid methyl ester

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