2-APB

SynDRA canonical compound SYN1947819 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	ITPR1 \| TRPC1 \| TRPC3 \| TRPC4 \| TRPC5 \| TRPC6 \| TRPC7 \| TRPM2 \| TRPM3 \| TRPM6 \| TRPV1 \| TRPV6
Mechanism of action	1,4,5-trisphosphate inhibitor

All known targets

TRPM2
TRPC7
TRPV1
TRPM6
TRPM3
TRPC1
TRPV6
TRPC6
TRPC5
TRPC4
TRPC3
TRPM7

Mechanisms of action (all sources)

1,4,5-trisphosphate inhibitor
TRPC1 BLOCKER (CHANNEL BLOCKER)
TRPV1 ACTIVATOR
TRPC6 BLOCKER (CHANNEL BLOCKER)
TRPC5 BLOCKER (CHANNEL BLOCKER)
TRPV2 ACTIVATOR
TRPC3 BLOCKER (CHANNEL BLOCKER)
TRPM6 ACTIVATOR
TRPM2 BLOCKER (CHANNEL BLOCKER)
TRPV6 ACTIVATOR
TRPV3 ACTIVATOR
TRPM3 INHIBITOR (GATING INHIBITOR)

Cross-references

PubChem CID: 1598
ChEBI: 131184
TTD: D00HCI

Synonyms

2-aminoethoxydiphenyl borate
2-aminoethoxydiphenylborane

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