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PF-228
SynDRA canonical compound SYN1950095 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CDK1 | CDK2 | CDK7 | GSK3B | IKBKB |
|---|
| Mechanism of action | focal adhesion kinase inhibitor |
|---|
All known targets
- CDK1
- CDK2
- CDK7
- GSK3B
- IKBKB
- PTK2
Mechanisms of action (all sources)
- FAK inhibitor
- CDK7 INHIBITOR
- IKBKB INHIBITOR
- CDK2 INHIBITOR
- PTK2 INHIBITOR
- CDK1 INHIBITOR
- GSK3B INHIBITOR
Cross-references
Synonyms
- PF 573228
- PF573228
- CHEMBL514554
- 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
- 6-((4-((3-(Methylsulfonyl)benzyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-3,4-dihydroquinolin-2(1H)-one
- 6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one
- 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one
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