← SynDRA

AMG458

SynDRA canonical compound SYN1970325 — structure-anchored drug synonym record

All known targets

• MET

Mechanisms of action (all sources)

• MET INHIBITOR

Cross-references

• PubChem CID: 24764449

Synonyms

• AMG 458
• 1-(2-Hydroxy-2-methylpropyl)-N-(5-((7-methoxyquinolin-4-yl)oxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• 4535RW5Y3A
• 1-(2-hydroxy-2-methylpropyl)-N-[5-(7-methoxyquinolin-4-yl)oxypyridin-2-yl]-5-methyl-3-oxo-2-phenylpyrazole-4-carboxamide
• 1-(2-hydroxy-2-methylpropyl)-N-[5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• 1H-Pyrazole-4-carboxamide, 2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-N-(5-((7-methoxy-4-quinolinyl)oxy)-2-pyridinyl)-5-methyl-3-oxo-2-phenyl-
• UNII-4535RW5Y3A
• 1-(2-hydroxy-2-methylpropyl)-N-{5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl}-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• Substituted Pyrazolone, 17
• AMG-458 (c-Met)
• MLS006010963
• SCHEMBL197714
• CHEMBL460472
• BDBM24466
• AMG-458,AMG458
• DTXSID80238521
• HMS3656H21
• BCP01917
• EX-A2447
• NSC754346
• s2747
• ZINC43194549
• AKOS027422876
• CCG-269954
• NSC-754346
• SB19374
• NCGC00346670-01
• NCGC00346670-05
• 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• AC-36075
• AS-16283
• HY-14723
• SMR004702767
• AMG-458(AMG458;AMG 458)
• CS-0003527
• FT-0752842
• SW220166-1
• A24894
• Q27258802